Multiplexed Imaging

Multiplexed Imaging

from Wang et al, Science 2018

Our goal is to add spatial resolution to cytometry-data in order to understand, in a tissue, WHERE immune and cancer cells interact

We design, develop and apply methods for multiplexed visualization of protein and RNA molecules in tissue sections.

To characterize the tissue architecture associated to dysfunctional states of the immune system in cancer settings, we make use of both confocal fluorescent microscopy and multiplexed secondary ion beam imaging.

We make use of barcoding systems that enable multi-parametric fluorescent imaging of proteins and RNAs.

We make use of NanoSIMs machine for multiplexed high-resolution imaging of intracellular structures.